Thursday, February 9, 2023

Victor Babeș (Romanian pronunciation

Victor Babeș (Romanian pronunciation: [ˈviktor ˈbabeʃ]; 28 July 1854 in Vienna – 19 October 1926 in Bucharest) was a Romanian physician, bacteriologist, academician and professor. One of the founders of modern microbiology, Victor Babeș is author of one of the first treatises of bacteriology in the world – Bacteria and their role in pathological anatomy and histology of infectious diseases, written in collaboration with French scientist Victor André Cornil in 1885.[1] In 1888, Babeș underlies the principle of passive immunity,[2] and a few years later enunciates the principle of antibiosis.[3] He made early and significant contributions to the study of rabies, leprosy, diphtheria, tuberculosis and other infectious diseases. He also discovered more than 50 unknown germs and foresaw new methods of staining bacteria and fungi.[4] Victor Babeș introduced rabies vaccination and founded serotherapy in Romania.[1]

Babeș-Bolyai University in Cluj-Napoca and the University of Medicine and Pharmacy in Timișoara bear his name.

Origin and family

Victor Babeș was the son of Vincențiu Babeș and Sophia Goldschneider.[5] His father was a Romanian magistrate, teacher, journalist and politician from the Banat region of Hungary, founding member of the Romanian Academic Society (22 April 1866) and President of History Section of the Romanian Academy (1898–1899).[6] One of the personalities who have distinguished themselves in the fight for the rights of Romanians in Transylvania, Vincențiu Babeș was repeatedly deputy in the Vienna Award and president of the Romanian National Party. Victor had a sister, Alma, and a brother, Aurel. The younger brother of Victor Babeș, Aurel, was a chemist and worked with Victor at the Institute of Bucharest. The son of Aurel, Aurel A. Babeș, was also a physician, and discovered a screening test for cervical cancer.

Victor Babeș was married to Iosefina Thorma, with whom he had a son, Mircea.[5]

Studies

In childhood, Victor Babeș was always attracted to poetry, music and especially literature, as well as performance sport, natural science and dramatics. He began studying dramatic arts in Budapest. The death of his sister, Alma, caused by tuberculosis, at a young age, led him to abandon started studies and enroll in medicine.[6] He attended the Faculty of Medicine in Budapest and Vienna. Victor received his doctorate in medicine in Vienna, in 1878. In 1881 he received a scholarship and went to Paris and Berlin, where he worked with leading teachers of the time: Cornil, Louis Pasteur, Rudolf Virchow, Robert Koch and others.[6] He continued to study with great teachers from Munich, Heidelberg, and Strasbourg until 1886.

Scientific activity

Bust of Victor Babeș in front of Babeș-Bolyai University in Cluj-Napoca
Stamp issued to commemorate the 125th anniversary of the founding of the Victor Babeș National Institute
The memorial Victor Babeș museum on Strada Andrei Mureșan in Bucharest

He began his scientific career as an assistant in the Pathological Anatomy laboratory from Budapest (1874–1881). In 1885 he was appointed professor of histopathology at the Faculty of Medicine in Budapest. The same year, he discovered a parasitic sporozoan of the ticks, named Babesia in his honor (of the family Babesiidae), and which causes a rare and severe disease called babesiosis. Later that year, he publishes the first treatise of bacteriology in the world, Bacteria and their role in pathological anatomy and histology of infectious diseases, which he co-authored with Cornil.[7]

Babeș's scientific endeavours were wide-ranging. He was the first to demonstrate the presence of tuberculous bacilli in the urine of infected patients. He also discovered cellular inclusions in rabies-infected nerve cells. Of diagnostic value, they were to be named after him (Babeș-Negri bodies). Babeș was the promoter of morphopathological conception about the infectious process, medical guidelines based on the synthesis between bacteriology and pathological anatomy. Babeș was credited with inventing the first rationalized model of thermostat[3] and some methods for staining bacteria and fungi in histological preparations and cultures.

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